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Beilstein J. Org. Chem. 2014, 10, 2065–2070, doi:10.3762/bjoc.10.214
Graphical Abstract
Figure 1: Synthesis of diamides, α-amino amides [13,14] and α-amino amidines [15-19] through Ugi and related MCRs.
Figure 2: Synthesis of imidazolopyridines 7a–d through a three-component coupling reaction of substituted ben...
Figure 3: A plausible reaction mechanism for the iodine-catalyzed α-amino amidine synthesis.